HLA (1)Gene
| Gene | Ameircan | European | Chinese | Total | |||
|---|---|---|---|---|---|---|---|
| Common | Well-documented | Common | Well-documented | Common | Well-documented | ||
| HLA-A | 63 | 171 | 34 | 185 | 26 | 128 | 421 |
| HLA-B | 123 | 228 | 62 | 258 | 58 | 158 | 572 |
| HLA-C | 41 | 93 | 32 | 165 | 28 | 91 | 303 |
| Allele | Crystal | Heterodimer |
|---|---|---|
| HLA-A | 81 | 59 |
| HLA-B | 170 | 112 |
| HLA-C | 6 | 44 |
| Gene | SNP |
|---|---|
| HLA-A | 20684 |
| HLA-B | 18719 |
Neoantigen（1）of
different tumors
| Gene | Peptides |
|---|---|
| HLA-A | 107336 |
| HLA-B | 200106 |
| HLA-C | 71974 |
| Cancer | Stsate=WT | Bind Level=WB | State=Mut | Bind Level=SB |
|---|---|---|---|---|
| blca | 16085 | 23877 | 15983 | 8181 |
| brca | 32273 | 46530 | 29482 | 15225 |
| coadread | 39645 | 57405 | 37387 | 19627 |
| gbm | 28009 | 40374 | 25585 | 13220 |
| hnsc | 34425 | 48667 | 31494 | 17252 |
| kirc | 20118 | 30074 | 19844 | 9888 |
| laml | 9912 | 15689 | 10710 | 4933 |
| luad | 46542 | 55580 | 38117 | 19079 |
| lusc | 30168 | 45426 | 30584 | 15326 |
| ov | 23056 | 33535 | 21714 | 11235 |
| ucec | 68141 | 98728 | 65352 | 34765 |
Mutation of
（1）HLA in tumors
| Mutation | HLA-A | HLA-B | HLA-C |
|---|---|---|---|
| DLCA | 6 | 3 | 1 |
| BRCA | 1 | 4 | 1 |
| CESC | 4 | 7 | 3 |
| COAD | 13 | 13 | 6 |
| HNSC | 19 | 21 | 2 |
| KIRC | 1 | ||
| KIRP | 1 | 1 | |
| LGG | 3 | 1 | |
| LUAD | 9 | 4 | 1 |
| LUSC | 10 | 3 | 1 |
| OV | 1 | ||
| PRAD | 1 | ||
| READ | 1 | 2 | |
| SKCM | 3 | 8 | 4 |
| STAD | 11 | 20 | 5 |
| THCA | 1 | ||
| UCEC | 6 | 7 | 5 |
| Cancer | SMG |
|---|---|
| BLCA | 13 |
| BRCA | 25 |
| COAD/READ | 27 |
| GBM | 16 |
| HNSC | 20 |
| KIRC | 11 |
| LAML | 16 |
| LUAD | 26 |
| LUSC | 18 |
| OV | 4 |
| UCEC | 38 |
| Gene | Mutation |
|---|---|
| C | 26 |
| P | 237 |
| PreC | 38 |
| PreS1 | 1 |
| PreS2 | 4 |
| S | 96 |
Transplant（1）HLA Alleles compared in 3DHLAMatch
| Allele | Common | Ameircan | Chinese | European |
|---|---|---|---|---|
| HLA-A | 69 | 63 | 26 | 34 |
| HLA-B | 133 | 123 | 58 | 62 |
| HLA-C | 48 | 41 | 28 | 32 |
| Gene | RMSD Record |
|---|---|
| HLA-A | 19388 |
| HLA-B | 78803 |
| HLA-C | 2353 |
| Gene | Risk Position |
|---|---|
| HLA-A | 14 |
| HLA-B | 25 |
| HLA-C | 15 |