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The number of mutation hotspots of top 15 genes in different cancer.
|
Number
|
SMG
|
Mutation
|
Cancer
|
|---|---|---|---|
| 1 | ACVR1B | A405V | lusc |
| 2 | ACVR1B | A405V | ucec |
| 3 | AKT1 | L52R | kirc |
| 4 | AKT1 | E17K | lusc |
| 5 | AKT1 | L52R | brca |
| 6 | AKT1 | E17K | brca |
| 7 | AKT1 | E17K | hnsc |
| 8 | APC | S2464Y | ucec |
| 9 | APC | A199V | ucec |
| 10 | APC | S1400L | ucec |
| 11 | APC | I2661 | ucec |
| 12 | APC | S2464Y | coadread |
| 13 | APC | A199V | coadread |
| 14 | APC | S1400L | coadread |
| 15 | AR | L57Q | lusc |
| 16 | AR | Q58L | ucec |
| 17 | AR | L57Q | hnsc |
| 18 | AR | Q58L | luad |
| 19 | AR | Q58L | hnsc |
| 20 | AR | Q58L | brca |
| 21 | AR | Q58L | blca |
| 22 | ARHGAP35 | R832Q | ucec |
| 23 | ARHGAP35 | E400K | ucec |
| 24 | ARHGAP35 | R832Q | brca |
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